Table 2 |
||||
|
Validation results for the InterVA model and PCVA against the HCOD in diagnosing the cause of death for the five most common causes of death among 145 adults |
||||
|
Causes of death |
Sensitivity (%) (95% CI) |
PPV (%) (95% CI) |
Specificity (%) (95% CI) |
NPV (%) (95% CI) |
|
|
||||
|
InterVA |
||||
|
HIV/AIDS-related death |
70 (5-84) |
61 (43-76) |
87 (79-92) |
91 (84-92) |
|
Cardiovascular |
52 (34-69) |
57 (37-75) |
88 (81-94) |
86 (78-92) |
|
Tuberculosis (pulmonary) |
83 (36-100) |
28 (10-54) |
91 (85-95) |
99 (96-100) |
|
Meningitis |
43 (10-82) |
33 (8-70) |
96 (91-99) |
97 (93-99) |
|
Diabetes |
63 (25-92) |
83 (36-100) |
99 (96-100) |
98 (94-100) |
|
PCVA |
||||
|
HIV/AIDS-related death |
88 (72-97) |
80 (64-92) |
94 (88-98) |
96 (91-99) |
|
Cardiovascular |
70 (51-84) |
82 (63-94) |
96 (90-99) |
91 (85-95) |
|
Tuberculosis (pulmonary) |
100 (54-100) |
55 (23-83) |
96 (92-99) |
100 (97-100) |
|
Meningitis |
43 (10-82) |
60 (15-95) |
99 (95-100) |
97 (93-99) |
|
Diabetes |
100 (63-100) |
57 (29-82) |
96 (91-99) |
100 (97-100) |
|
|
||||
|
PCVA: physician-certified verbal autopsy; InterVA model: probabilistic model; NPV: negative predictive value; PPV: positive predictive value; CI: confidence interval PPV is the number of positives correctly diagnosed through the InterVA model/PCVA (true positives) divided by number of positives diagnosed in hospital (as the gold standard). NPV is the number of negatives correctly diagnosed through the InterVA model/PCVA (true negatives) divided by number of negatives diagnosed in hospital (as the gold standard). |
||||
|
Bauni et al. Population Health Metrics 2011 9:49 doi:10.1186/1478-7954-9-49 |
||||
